Lv7
5000 积分 2023-02-05 加入
Design and Optimization of Lysosome-Targeted β-Galactoside Senolytic Prodrugs: Harnessing the Aromatic Ring of Self-Immolative Linkers
25天前
已完结
New Life for an Old Target: Melanin Concentrating Hormone (MCH) R1 Antagonists for Obesity
25天前
已完结
A Small-Molecule Platform Demonstrates Light-Activated Synergy Between Cuproptosis and Photodynamic Tumor Therapy
25天前
已完结
An Optimized Route to the Syringolin Natural Products Enables Combinatorial Synthesis of Selective, Bioactive Inhibitors of the Plasmodium falciparum 20S Proteasome
25天前
已完结
Discovery of FLC-8 as the First Covalent FLT3 Inhibitor Targeting Cys807 for FLT3 Mutant Acute Myeloid Leukemia
25天前
已完结
Discovery of Non-prostanoid EP4 Agonists for the Treatment of Inflammatory Bowel Disease
25天前
已完结
Discovery of Highly Potent and Selective IKZF2 Degraders for Cancer Immunotherapy
25天前
已完结
Development of Structurally Simplified, Non-azadecalin Glucocorticoid Antagonists which Demonstrate In Vivo Activity
25天前
已完结
Structure-Based Discovery of Imidazo[4,5- c ]pyridine SARM1 Modulators Showing Paradoxical Activation
25天前
已完结
Nanoscale direct-to-biology optimization of Cdk2 inhibitors
25天前
已完结
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