Lv21
168 积分 2023-02-28 加入
Revisiting the hERG safety margin after 20 years of routine hERG screening
1小时前
已完结
Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development
4小时前
已完结
An Innovative Approach to Optimize First‐In‐Human Minimal Anticipated Biological Effect Level Based Starting Dose in Oncology Trials for Bispecific T‐Cell Engagers: Experience from A Solid Tumor Bispecific T‐Cell Engager
6天前
已完结
A comprehensive review of 20 years of progress in nonclinical QT evaluation and proarrhythmic assessment
14天前
已完结
Toxicologic Pathology Forum*: Opinion on Qualitative Severity Descriptors to Express Magnitude of Changes in Clinical Pathology Endpoints in Nonclinical Toxicity Studies
1个月前
已完结
In vivo CAR engineering for immunotherapy
1个月前
已完结
Tumour-derived small extracellular vesicles act as a barrier to therapeutic nanoparticle delivery
1个月前
已完结
In vivo chimeric antigen receptor (CAR)-T cell therapy
1个月前
已完结
Exploratory assessment of dose proportionality: review of current approaches and proposal for a practical criterion
1个月前
已完结
Everds, NE et al. (2013). Interpreting Stress Responses during Routine Toxicity Studies: A Review of the Biology, Impact, and Assessment. Toxicol
2个月前
已完结
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