Lv54
910 积分 2021-02-02 加入
Discovery of WDR5–MLL1 and HDAC Dual-Target Inhibitors for the Treatment of Acute Myeloid Leukemia
34分钟前
待确认
Selectively triggered: ROS-activated Michael acceptor prodrug strategy to enhance tumor targeting efficacy
1天前
待确认
Thiazole-Linked N -Hydroxypropanamide Derivatives: Selective HDAC6 Inhibitors with Therapeutic Potential for Neurodegenerative Diseases
2天前
已完结
CRIF1 deficiency induces FOXP3 LOW inflammatory non-suppressive regulatory T cells, thereby promoting antitumor immunity
6天前
已完结
A Hypoxia-Activated Photomolecular Glue with Synergistic Cyclin K Degradation and Phototherapy for Cancer Treatment
6天前
已完结
Trends in target novelty in oncology R&D
2个月前
已完结
Discovery of Highly Selective CYP1B1 Inhibitors
2个月前
已完结
Rational Design of Novel Quinazolinone–Pyrrolodihydropyrrolone Analogs as PIM/HDAC Dual-Target Inhibitors for the Treatment of Acute Myelocytic Leukemia
3个月前
已完结
Inhibition of HIPK3 by AST487 Ameliorates Mutant HTT-Induced Neurotoxicity and Apoptosis via Enhanced Autophagy
3个月前
已完结
CDK10 suppresses nucleic acid sensors-mediated antitumor immunity
4个月前
已完结
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