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46 积分 2023-05-23 加入
Pathway-selective 5-HT1AR agonist speeds up antidepressant effect
1个月前
已完结
Targeting cytokines and signaling molecules related to immune pathways in atopic dermatitis: therapeutic implications and challenges
2个月前
已完结
Design, synthesis, and biological evaluation of novel sesquiterpene lactone derivatives as PKM2 activators with potent anti-ulcerative colitis activities
2个月前
已完结
PKM2: A novel helmsman of lipid metabolism
2个月前
已完结
CGRP Targeting Therapy for Chronic Migraine—Evidence from Clinical Trials and Real-world Studies
2个月前
已完结
Cryo-EM structure enabling virtual screening for the discovery of highly potent TRPM3 antagonists with analgesic efficacy
2个月前
已完结
Discovery of HZS60 as a Novel Brain Penetrant NMDAR/TRPM4 Interaction Interface Inhibitor with Improved Activity and Pharmacokinetic Properties for the Treatment of Cerebral Ischemia
2个月前
已完结
Safety and efficacy of a novel ANGPTL4 inhibitory antibody for lipid lowering: results from phase 1 and phase 1b/2a clinical studies
2个月前
已完结
Discovery and Development of NLRP3 Inhibitors Targeting the LRR Domain to Disrupt NLRP3-NEK7 Interaction for the Treatment of Rheumatoid Arthritis
3个月前
已完结
Discovery of Clinical Candidate NT-0796, a Brain-Penetrant and Highly Potent NLRP3 Inflammasome Inhibitor for Neuroinflammatory Disorders
3个月前
已完结
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