Lv3
330 积分 2023-06-16 加入
CDK2 heterobifunctional degraders co-degrade CDK2 and cyclin E resulting in efficacy in CCNE1-amplified and overexpressed cancers
24天前
已完结
Discovery of Atirmociclib (PF-07220060): A Potent and Selective CDK4 Inhibitor
1个月前
已完结
Structural basis of T-loop–independent recognition and activation of CDKs by the CDK-activating kinase
4个月前
已完结
Selective Reduction of Cysteine Mutant Antibodies for Site-Specific Antibody–Drug Conjugates
8个月前
已完结
An allosteric cyclin E-CDK2 site mapped by paralog hopping with covalent probes
8个月前
已完结
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