Lv4
518 积分 2025-03-28 加入
HDAC11 Inhibition as a Potential Therapeutic Strategy for AML: Target Identification, Lead Discovery, Antitumor Potency, and Mechanism Investigation
1天前
已完结
Discovery of a Hydroxamic Acid-Based HDAC11 Isoform-Selective Inhibitor with Oral Anti-AML Potency
2天前
已完结
Discovery and Characterization of Novel BLIMP-1 Heterobifunctional Ligand-Directed Degraders
3个月前
已完结
Discovery and Development of a Small-Molecule Inhibitor Targeting the GAS41 YEATS Domain in Nonsmall Cell Lung Cancer
3个月前
已完结
Discovery of APS03118, a Potent and Selective Next-Generation RET Inhibitor with a Novel Kinase Hinge Scaffold
5个月前
已完结
Discovery of GDC-0077 (Inavolisib), a Highly Selective Inhibitor and Degrader of Mutant PI3Kα
6个月前
已完结
Synthesis of (Hetero)biaryls via Nickel Catalyzed Reductive Cross‐Electrophile Coupling Between (Hetero)aryl Iodides and Bromides
7个月前
已完结
Structure-Guided Optimization Provides a Series of TTK Protein Inhibitors with Potent Antitumor Activity
7个月前
已完结
Dearomative Pyrrole (3 + 2) Reaction with Geminal Bromonitroalkane: Synthesis of 2,3-Dihydropyrroles
8个月前
已完结
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