Lv3
240 积分 2022-05-17 加入
CS12192, a novel JAK3/JAK1/TBK1 inhibitor, attenuates autoimmune dermatoses in murine models
3天前
已完结
TBK1 pharmacological inhibition mitigates osteoarthritis through attenuating inflammation and cellular senescence in chondrocytes
3天前
已完结
Design and Pharmacology of N-[(3R)-1,2,3,4-Tetrahydroisoquinolinium- 3-ylcarbonyl]-(1R)-1-(4-chlorobenzyl)- 2-[4-cyclohexyl-4-(1H-1,2,4-triazol- 1-ylmethyl)piperidin-1-yl]-2-oxoethylamine (1), a Potent, Selective, Melanocortin Subtype-4 Receptor Agonist
1个月前
已完结
Ruxolitinib alleviated muscle atrophy in cancer cachexia by inhibiting IL-6/JAK/STAT3 signaling pathway in mice
1个月前
已完结
Oxalyl Boronates Enable Modular Synthesis of Bioactive Imidazoles
6个月前
已完结
Discovery of a Potent Dual SLK/STK10 Inhibitor Based on a Maleimide Scaffold
6个月前
已完结
Design, synthesis and biological evaluation of bisnoralcohol derivatives as novel IRF4 inhibitors for the treatment of multiple myeloma
7个月前
已完结
Discovery and Characterization of Allosteric WNK Kinase Inhibitors
8个月前
已完结
Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria
9个月前
已完结
Discovery of BAY-985, a Highly Selective TBK1/IKKε Inhibitor
9个月前
已完结
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