| 标题 |
Factors contributing to fracture in pernicious anemia patients presenting with symptomatic subacute vertebral compression fractures
恶性贫血伴症状性亚急性椎体压缩性骨折患者的骨折因素
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| 其它 | 摘要：Background/Purpose : Pernicious anemia (PA) has been associated with both low spine BMD and increased fracture risk in retrospective cohort studies. The cause of these observations is obscure. The purpose of this study is to describe and compare the clinical details of a cohort of PA patients who presented with subacute vertebral compression fractures (SVCF) to one without PA. Methods : A retrospective cohort study was conducted from a population of 165 patients presenting with SVCF to an outpatient fracture clinic. The clinical characteristics of 30 PA patients diagnosed at the time of presentation, based on low vitamin B12 levels and the presence of either intrinsic factor (IF) or anti-parietal cell antibodies (APCA), was compared to the remaining 135 without PA. |
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