| 标题 |
Pernicious anemia presenting with symptomatic vertebral compression fractures
恶性贫血伴症状性椎体压缩性骨折
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| 其它 | 摘要“Objective: Pernicious anemia (PA) has been associated with both low spine BMDand increased fracture risk in retrospective cohort studies. The cause of these observations is obscure. The purpose of this study is to describe and compare the clinical details of a cohort of PA patients who presented with subacute vertebral compression fractures (SVCF) to one without PA. Methods: A retrospective cohort study was conducted from a population of 159 patients presenting with SVCF to an outpatient fracture clinic. 24 patients with PA diagnosed at the time of presentation, based on low vitamin B12 levels and the presence of either intrinsic factor (IF) or anti parietal cell antibodies (APCA), were compared to the remaining 135 patients without PA. |
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