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 Protective Effects of Copper Chaperone for Cu,Zn-SOD (CCS) Against Ischemic Neuronal Damage in the Focal Cerebral Ischemia in Rat |
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K. Yoo, O. Park, Jung-Hoon Choi, C. H. Lee, Hyung-Cheul Shin, Dae-Won Kim, I. Hwang, Soo-Young Choi, Sang-hyun Lee, M. Won less Published 1 March 2009 Medicine Laboratory Animal Research 저자정보 Ki-Yeon Yoo Ok Kyu Park Jung Hoon Choi Chung Hyun Lee Hyung-Cheul Shin Dae Won Kim In Koo Hwang Soo Young Choi Sang Hyun Lee Moo-Ho Won 저널정보 한국실험동물학회 Laboratory Animal Research Laboratory Animal Research Vol.25 No.1 발행연도 2009.3 수록면 69 - 73 (5page) TLDR The result suggests that CCS is essential to activate SOD, and that transduction of PEP-1-CCS provides a potential strategy for therapeutic delivery in various diseases including stroke related to SOD or ROS. Abstract Reactive oxygen species (ROS) contribute to the development of various diseases in humans. Cu,Znsuperoxide dismutase (SOD) is one of major means by which cells counteract the deleterious effects of ROS. |
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