| 标题 |
  Antibody level comparison after porcine epidemic diarrhea vaccination via different immunization routes 相关领域
接种疫苗
免疫
医学
抗体
免疫学
病毒学
肌肉注射
中和抗体
猪流行性腹泻病毒
腹泻
病毒
内科学
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| 网址 | |
| DOI | |
| 其它 |
作者列表：C Hu 1, X Xie 2, D Zhao 3, H Liu 1, X Liu 4, T Yang 5, W Sun 6 摘要：Porcine epidemic diarrhea (PED) is a disease extremely harmful to pig health. Intramuscular and Houhai acupoint injections are the main immunization routes to prevent and control PED. This study aimed to evaluate the efficacy of these two routes in pregnant sows based on serum IgG, IgA, and neutralizing antibody levels. PED virus (PEDV) immunoprophylaxis with live-attenuated and inactivated vaccines was administered. The vaccinations for the intramuscular injections elevated IgG and neutralizing antibody levels more than Houhai acupoint injections at most timepoints after immunization. However, the anti-PEDV IgA antibodies induced by vaccination with the two immunization routes did not differ significantly. In conclusion, intramuscular injections are better than Houhai acupoint injections for PEDV vaccination of pregnant sows. |
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