| 标题 |
Efficacy of calcitriol in treatment of diabetic leukoaraiosis patients with mild cognitive impairment
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作者：Zhao, X.H., Zhu, Y.P., Yang, J. & Liu, H.Q. 摘要：To assess the effect of calcitriol for diabetic leukoaraiosis patients with mild cognitive impairment (MCI). Methods: A total of 256 patients with diabetic leukoaraiosis were consecutively enrolled in this study, of which 181 cases were diagnosed as MCI, and were divided into two groups: control group (n=85), and intervention group (n=88). Patients in intervention group received Calcitriol (0.25ug/day) treatment for 12 months. Cognitive function was assessed using Montreal cognitive assessment (MoCA) scale at baseline, 6 months' and 12 months' follow-up. Results: A number of 181 cases were randomly divided into control group and intervention group. After 12 months, 173 cases (85 in control group, 88 in intervention group) completed the follow up. In intervention group, MoCA scores were not significantly improved at 6M ((18.84±2.08 vs. 19.23±2.42, NS), |
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(2025-6-4)
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