Recent Advance of Transition Metal-Free Catalyzed Suzuki-Type Cross Coupling Reaction

Transition metal catalyzed Suzuki coupling reaction serves as one of the most versatile and widespread methods for the C-C bonds formation, which greatly promotes the development of synthetic chemistry.Currently, the Suzuki coupling reactions heavily rely on noble palladium-catalyzed system.However, the high cost, toxicity and low reserves of palladium have become the main obstacles for their development in organic synthesis.Over the past two decades, metal-free catalyzed Suzuki-Type cross coupling reactions earned extensive concern, and a large number of efficient and new reaction systems have been reported.In this review, the recent progresses of metal-free catalyzed Suzuki-Type cross coupling reactions are summarized, mainly including bases, organometallic reagents and organic molecules promoted reactions.In addition, the mechanism of reaction is also discussed in this review.