医学
混淆
观察研究
狂饮
冲程(发动机)
疾病
冠状动脉疾病
随机对照试验
心力衰竭
心源性猝死
饮酒量
环境卫生
内科学
酒
伤害预防
毒物控制
化学
工程类
机械工程
生物化学
作者
Mariann R. Piano,Gregory M. Marcus,Dawn M. Aycock,Jennifer F. Buckman,Chueh‐Lung Hwang,Susanna C. Larsson,Kenneth J. Mukamal,Michael Roerecke
出处
期刊:Circulation
[Lippincott Williams & Wilkins]
日期:2025-06-09
标识
DOI:10.1161/cir.0000000000001341
摘要
Alcohol is one of the most commonly consumed substances in the world, exhibiting complex relationships with multiple aspects of cardiovascular health and disease. The majority of the research on the topic is observational and therefore prone to bias and confounding. The available evidence suggests no risk to possible risk reduction when alcohol is consumed in low amounts (such as no more than 1 to 2 drinks a day) in regard to coronary artery disease, stroke, sudden death, and possibly heart failure. The risk associated with consuming 1 to 2 drinks a day on atrial fibrillation remains unknown. More randomized trials of low to moderate alcohol consumption are needed for more definitive conclusions. In stark contrast, heavier alcohol consumption such as binge drinking or consuming on average ≥3 drinks/d is consistently associated with worse outcomes in every cardiovascular disease entity studied. Considering the level of evidence, it remains unknown whether drinking is part of a healthy lifestyle and therefore clinicians should reinforce healthy lifestyle behaviors such as regularly engaging in physical activity, avoiding tobacco use, and maintaining healthy body weight.
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