Tranexamic acid in total knee arthroplasty

AnaesthesiaVolume 78, Issue 3 p. 275-278 Editorial Tranexamic acid in total knee arthroplasty C. R. Bailey, Corresponding Author C. R. Bailey Consultant [email protected] @@DocCRBailey Department of Anaesthesia, Guy's and St. Thomas' NHS Foundation Trust, London, UK Correspondence to: C. R. Bailey Email: [email protected]Search for more papers by this author C. R. Bailey, Corresponding Author C. R. Bailey Consultant [email protected] @@DocCRBailey Department of Anaesthesia, Guy's and St. Thomas' NHS Foundation Trust, London, UK Correspondence to: C. R. Bailey Email: [email protected]Search for more papers by this author First published: 04 January 2023 https://doi.org/10.1111/anae.15960 This editorial accompanies an article by Hsu L-I et al., Anaesthesia 2023; 78: 303–14. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1Tengborn L, Blombäck M, Berntorp E. Tranexamic acid--an old drug still going strong and making a revival. Thrombosis Research 2015; 135: 231–42. 2 World Health Organization. Model list of essential medicines. https://list.essentialmeds.org (accessed 01/11/2022). 3Shah A, Bailey CR. Outcomes following surgery: are we measuring what really matters? Anaesthesia 2019; 74: 696–9. 4Alshryda S, Sarda P, Sukeik M, Nargol A, Blenkinsopp J, Mason JM. 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Intra-articular vs. intravenous administration: a meta-analysis of tranexamic acid in primary total knee arthroplasty. Journal of Orthopaedic Surgery and Research 2020; 15: 581. 13Ling T, Zhang L, Huang L. The efficacy and safety of combined administration of intravenous and intra-articular tranexamic acid in total knee arthroplasty: an update meta-analysis. Journal of Clinical Pharmacology and Therapeutics 2022; 47: 1312–21. 14Bansal RA, Nicholas A, Bansal AS. Tranexamic acid: an exceedingly rare cause of anaphylaxis during anaesthesia. Case Reports in Immunology 2016; 7828351. 15Lucas-Polomeni M-M, Delaval Y, Menestret P, Delaval P, Ecoffey C. A case of anaphylactic shock with tranexamique acid (Exacyl). Annals Francaises d'Anesthesie et de Reanimation 2004; 23: 607–9. 16Patel S, Robertson B, McConachie I. Catastrophic drug errors involving tranexamic acid administered during spinal anaesthesia. Anaesthesia 2019; 74: 904–14. 17Palanisamy A, Kinsella SM. Spinal tranexamic acid – a new killer in town. Anaesthesia 2019; 74: 831–3. 18Murao S, Nakata H, Roberts I, Yamakawa K. Effect of tranexamic acid on thrombotic events and seizures in bleeding patients: a systematic review and meta-analysis. Critical Care 2021; 25: 380. 19Lecker I, Wang DS, Whissell PD, Avramescu S, Mazer CD, Orser BA. Tranexamic acid-associated seizures: causes and treatment. Annals of Neurology 2016; 79: 18–26. 20Alameel T, West M. Tranexamic acid treatment of life-threatening hematuria in polycystic kidney disease. International Journal of Nephrology 2011; 2011: 203579. 21Ko DH, Kim TH, Kim JW, Gu JJ, Yoon BH, Oh JH, Hong SG. Tranexamic acid-induced acute renal cortical necrosis in post-endoscopic papillectomy bleeding. Clinical Endoscopy 2017; 50: 609–13. 22 Royal Medical Colleges. Tranexamic acid to be used to reduce blood loss in surgery. September/October 2022. https://mag.nationalhealthexecutive.com/?m=62920&i=761611&p=44&ver=html5 (accessed 01/11/2022). 23Devereaux PJ, Marcucci M, Painter TW, et al. Tranexamic acid in patients undergoing noncardiac surgery. New England Journal of Medicine 2022; 386: 1986–97. 24 NHS Blood and Transplant. Amber alert issued on blood stocks – existing O neg and O pos donors asked to make appointments. October 2022. https://www.blood.co.uk/news-and-campaigns/news-and-statements/amber-alert-issued-on-blood-stocks-existing-o-neg-and-o-pos-donors-asked-to-make-appointments/ (accessed 01/11/2022). 25 Royal College of Anaesthetists. NHSBT amber alert and use of tranexamic acid. October 2022. https://rcoa.ac.uk/news/nhsbt-amber-alert-use-tranexamic-acid?utm_source=President%27 s+News&utm_campaign=511bd369d9-Presidents-News-26-October-2022&utm_medium=email&utm_term=0_877bde7a06-511bd369d9-132204865 (accessed 01/11/2022). 26Klein AA, Bailey CR, Charlton AJ, et al. Association of Anaesthetists guidelines: cell salvage for peri-operative blood conservation 2018. Anaesthesia 2018; 73: 1141–50. 27 British National Formulary. Tranexamic acid. https://bnf.nice.org.uk/drugs/tranexamic-acid/medicinal-forms/ (accessed 01/11/22). 28 NHS Blood and Transplant. Blood transfusion: information to help patients prepare for treatment. 2022. https://www.nhsbt.nhs.uk/what-we-do/blood-services/blood-transfusion/ (accessed 01/11/2022). 29 Royal College of Anaesthetists. Disruption to the supply of remifentanil 2022. https://www.rcoa.ac.uk/news/disruption-supply-remifentanil (accessed 24/11/2022). Volume78, Issue3March 2023Pages 275-278 ReferencesRelatedInformation