Palladium/copper-cocatalyzed three-component tandem cyclization of o-alkenyl arylisocyanides, sulfur ylides with alcohols: direct synthesis of spiro 3,3’-cyclopropyl oxindoles

A novel palladium/copper-cocatalyzed three-component tandem cyclization of o-alkenyl arylisocyanides, sulfur ylides with alcohols has been developed for the first time. The reaction provides a simple and efficient method for the...