Effects of vision therapy on near exodeviation in children with convergence insufficiency treated during the convergence insufficiency treatment trials

Abstract Purpose To report the change in the magnitude of near exodeviation in children with symptomatic convergence insufficiency successfully treated with office‐based vergence/accommodative therapy in the Convergence Insufficiency Treatment Trial–Attention and Reading Trial. Methods A total of 131 children 9–14 years of age with symptomatic convergence insufficiency classified as successfully treated with office‐based vergence/accommodative therapy at the 16‐week outcome visit were included. Masked examiners measured the near ocular deviation by the prism and alternate cover test at baseline, primary outcome and 1‐year post‐treatment. The mean change in near deviation was calculated from baseline to primary outcome, from primary outcome to 1‐year post‐treatment and from baseline to 1‐year post‐treatment. Results Of the 131 participants successfully treated with vergence/accommodative therapy, 120 completed the 1‐year post‐treatment visit. A significant change in near exodeviation was observed at baseline to primary outcome (2.6Δ less exo, p < 0.001, moderate effect size d = 0.61) and at baseline to 1‐year post‐treatment (2.0Δ less exo; p < 0.001, small effect size d = 0.45). The change from primary outcome to 1‐year post‐treatment (0.6Δ more exo; p = 0.06, small effect size d = 0.11) was not significant. Forty per cent (48/120) of participants had a decrease in near exodeviation >3.5∆ (expected test/retest variability) between baseline and the primary outcome examination. Of the 120 participants, one (1.0%) was esophoric at the primary outcome and was subsequently exophoric at 1‐year post‐treatment. Four participants (3.3%) who were orthophoric or exophoric at the primary outcome were esophoric (all ≤3∆) at the 1‐year post‐treatment visit. Conclusion On average, the near exodeviation was smaller in size immediately after the discontinuation of vergence/accommodative therapy (2.6∆, moderate effect size) and 1 year post vergence/accommodative therapy (2.0∆, small effect size) in children with convergence insufficiency who were successfully treated; 40% had a clinically meaningful decrease in exophoria. The development of near esophoria was rare.