组织工程
肌腱
软骨
3D生物打印
生物医学工程
计算机科学
移植
生物相容性材料
材料科学
解剖
医学
外科
作者
Mine Altunbek,Ferdows Afghah,Özüm Şehnaz Çalışkan,James J. Yoo,Bahattin Koç
出处
期刊:Biofabrication
[IOP Publishing]
日期:2023-02-14
卷期号:15 (2): 022002-022002
被引量:3
标识
DOI:10.1088/1758-5090/acb73d
摘要
Tissue interfaces include complex gradient structures formed by transitioning of biochemical and mechanical properties in micro-scale. This characteristic allows the communication and synchronistic functioning of two adjacent but distinct tissues. It is particularly challenging to restore the function of these complex structures by transplantation of scaffolds exclusively produced by conventional tissue engineering methods. Three-dimensional (3D) bioprinting technology has opened an unprecedented approach for precise and graded patterning of chemical, biological and mechanical cues in a single construct mimicking natural tissue interfaces. This paper reviews and highlights biochemical and biomechanical design for 3D bioprinting of various tissue interfaces, including cartilage-bone, muscle-tendon, tendon/ligament-bone, skin, and neuro-vascular/muscular interfaces. Future directions and translational challenges are also provided at the end of the paper.
科研通智能强力驱动
Strongly Powered by AbleSci AI