组学
生殖系
冠状动脉疾病
体细胞
疾病
精密医学
生物
造血
种系突变
表型
计算生物学
生物信息学
医学
遗传学
突变
干细胞
内科学
基因
作者
Tetsushi Nakao,Pradeep Natarajan
标识
DOI:10.1038/s44161-022-00154-1
摘要
Studies of the genetic architecture of cardiovascular disease once focused on heritable germline factors. Newer work has shed light on the role of somatic mutations in blood cells. These mechanistic and multi-omics studies, along with phenotypic analyses, offer the prospect of new precision cardiovascular medicine paradigms.
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