Generation of New Synthons for Synthesis Through Activation of Nitromethane

Nitromethane is used as a common solvent, stabilizer, and fuel additive. Nitromethane has also been used as a sustainable building block and convenient reagent in chemical synthesis. In this Minireview, we summarize the recent advances in activation of nitromethane, using nitromethane as the source of cyano group, nitrogen, methylamine, formyl group, C1, nitroso, and oxime.