小干扰RNA
RNA干扰
领域(数学分析)
化学
细胞生物学
计算生物学
生物
核糖核酸
生物化学
数学
基因
数学分析
作者
Álvaro Somoza,Montserrat Terrazas,Ramón Eritja
摘要
Chemical modifications aimed at stabilizing the interaction between the 3'-end of siRNAs and the PAZ domain of RISC have been tested for their effect on RNAi activity. Such modifications contribute positively to the stability of siRNAs in human serum.
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