计算生物学
个性化医疗
集合(抽象数据类型)
选择(遗传算法)
医学
精密医学
序列(生物学)
生物信息学
计算机科学
生物
病理
人工智能
遗传学
程序设计语言
作者
Alberto Veiga,Francisco Queipo,Germán Bou,Alfonso Cepeda‐Emiliani,Ángel Concha
出处
期刊:Elsevier eBooks
[Elsevier]
日期:2022-01-01
卷期号:: 207-230
标识
DOI:10.1016/b978-0-323-90055-3.00049-1
摘要
Different oncogenes that act in different phases of the epithelium–adenoma–carcinoma sequence are involved in the development of colorectal carcinoma. Although this sequence is perfectly known, so far it is only possible to act on specific points of the set of known genetic alterations. Therapies aimed at neutralizing the effects of these alterations form the basis of personalized medicine or precision medicine. In this chapter, concepts closely related to these therapeutic strategies are analyzed, bringing us closer to the necessary knowledge of different types of biomarkers, key targets that currently mark treatment options, essential information to make an adequate patient selection, and the progress and challenges that arise in the short and medium term.
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