Conformation-dominated surface antifouling and aqueous lubrication

Antifouling and aqueous lubrication are important properties for biomaterials, especially for those with implantation purposes. In order to better understand the polymer conformation dependence of the surface antifouling and lubrication properties, poly(ethylene glycol) (PEG) polymers with mono-functional and difunctional catechol anchors were designed and anchored on surface to adopt tail and loop conformations. Diblock and triblock copolymers with poly(dopamine methacrylamide) (PDMA) block as anchors and PEG block as the main body were synthesized and anchored on silicon surfaces by a "grafting to" strategy. The chemical composition, film thickness, and surface roughness of both coatings were controlled to be similar to give a direct comparison of looped brushes and tailed analogues. Then, the antifouling and surface friction behaviors were detected to verify the topological conformation effect of PEG polymer brushes. Results showed that PEG triblock copolymer modified surface exhibited an obviously better antifouling property and a lower friction coefficient of ∼0.011 than that of PEG diblock copolymer modified surface. Additionally, calculation and simulation results demonstrated that triblock copolymer had higher adsorption energy and anchored on surface with looped conformation. It is indicated that the strongly anchored PEG loops are effective for excellent antifouling and lubricating properties due to its strong hydration and steric hindrance. The conformation-dominated enhanced antifouling and reduced interfacial friction is an effective method for the development of excellent antifouling surfaces.