Synthesis Methods for Halogenated Calix[4]Arenes

This review presents synthesis methods for halogenated calix[4]arenes at the upper rim and in meta-position of phenolic unit as well as at the lower rim by substitution of hydroxyl group by halogen atom; methods for introducing the atom of iodine, bromine and chlorine into the molecule of calix[4]arenes; the advantages and disadvantages of each method. Keywords: Bromination, Calix[4]arenes, chlorination, fluorination, halogenation, iodination, ipso-iodination.