医学
2019年冠状病毒病(COVID-19)
病危
2019-20冠状病毒爆发
严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)
疾病严重程度
危重病
重症监护医学
梅德林
内科学
病理
疾病
爆发
传染病(医学专业)
政治学
法学
作者
Eun Jin Kim,Yong Hoon Lee,Jae Seok Park,Jaehee Lee,Shin Yup Lee,Yeonjae Kim,Yong Shik Kwon,Jong Geol Jang,Kyeong‐Cheol Shin,Kyung Chan Kim,Eun Young Choi
出处
期刊:Medicine
[Ovid Technologies (Wolters Kluwer)]
日期:2021-02-19
卷期号:100 (7): e24437-e24437
被引量:7
标识
DOI:10.1097/md.0000000000024437
摘要
To describe the clinical and demographic characteristics of critically ill patients with COVID-19 in Daegu, South Korea, and to explore the risk factors for in-hospital mortality in these patients. Retrospective cohort study of 110 critically ill patients with COVID-19 admitted to the ICU in Daegu, South Korea, between February 18 and April 5, 2020. The final date of follow-up was April 20, 2020. A total of 110 patient medical records were reviewed. The median age was 71 years (interquartile range [IQR] = 63–78 years). During the study period, 47 patients (42.7%) died in the hospital. The most common SARS-CoV-2 infection related complication was acute respiratory distress syndrome (ARDS) in 95 patients (86.4%). Of the 79 patients (71.8%) who received invasive mechanical ventilation, 46 (58.2%) received neuromuscular blockade injection, and 19 (24.1%) received ECMO treatment. All patients received antibiotic injection, 99 patients (90%) received hydroxychloroquine, 96 patients (87.3%) received lopinavir-ritonavir antiviral medication, and 14 patients (12.7%) received other antiviral agents, including darunavir-cobicistat and emtricitabine-tenofovir. In the multivariable logistic regression model, the odds ratio of in-hospital death was higher with APACHE II score (OR = 1.126; 95% CI = 1.014–1.252; P= .027). The in-hospital mortality rate of critically ill patients with COVID-19 was approximately 40%. Higher APACHE II score at admission was an independent risk factor for death in these patients.
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