胶质瘤
甲基化
癌症研究
异柠檬酸脱氢酶
甲基转移酶
生物
医学
DNA甲基化
切除术
化学
价值(数学)
临床意义
分子生物学
预测值
细胞培养
免疫组织化学
抑制器
发起人
IDH1
作者
Gilbert Youssef,Elisa Aquilanti,Julie J. Miller,Zhou Lan,Aleksandra B Lasica,Isabel Arrillaga‐Romany,Tracy T. Batchelor,Tamar Berger,Rameen Beroukhim,Ugonma Chukwueke,Jörg Dietrich,Deborah Forst,Elizabeth R. Gerstner,L. Nicolas Gonzalez Castro,Justin T. Jordan,J Ricardo McFaline-Figueroa,Eudocia Q. Lee,Lakshmi Nayak,Vihang Nakhate,Juan Pablo Ospina
标识
DOI:10.1093/neuonc/noaf287
摘要
MGMTp methylation was not associated with a prognostic or predictive value in our IDH-mutant glioma cohort. CDKN2A/B status and extent of resection were strong predictors of outcomes.
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