自噬
生物
细胞生物学
袋3
机制(生物学)
胞浆
计算生物学
遗传学
生物化学
细胞凋亡
酶
认识论
哲学
作者
Lorenzo Galluzzi,Douglas R. Green
出处
期刊:Cell
[Elsevier]
日期:2019-06-01
卷期号:177 (7): 1682-1699
被引量:593
标识
DOI:10.1016/j.cell.2019.05.026
摘要
Macroautophagy (herein referred to as autophagy) is an evolutionary ancient mechanism that culminates with the lysosomal degradation of superfluous or potentially dangerous cytosolic entities. Over the past 2 decades, the molecular mechanisms underlying several variants of autophagy have been characterized in detail. Accumulating evidence suggests that most, if not all, components of the molecular machinery for autophagy also mediate autophagy-independent functions. Here, we discuss emerging data on the non-autophagic functions of autophagy-relevant proteins.
科研通智能强力驱动
Strongly Powered by AbleSci AI