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Mortality Associated With Sleep Duration and Insomnia

失眠症 医学 药丸 危险系数 睡眠(系统调用) 比例危险模型 睡眠开始 睡眠障碍 精神科 内科学 置信区间 计算机科学 药理学 操作系统
作者
Daniel F. Kripke,Lawrence Garfinkel,Deborah L. Wingard,Melville R. Klauber,Matthew Marler
出处
期刊:Archives of General Psychiatry [American Medical Association]
卷期号:59 (2): 131-131 被引量:1620
标识
DOI:10.1001/archpsyc.59.2.131
摘要

Patients often complain about insufficient sleep or chronic insomnia in the belief that they need 8 hours of sleep. Treatment strategies may be guided by what sleep durations predict optimal survival and whether insomnia might signal mortality risks.In 1982, the Cancer Prevention Study II of the American Cancer Society asked participants about their sleep duration and frequency of insomnia. Cox proportional hazards survival models were computed to determine whether sleep duration or frequency of insomnia was associated with excess mortality up to 1988, controlling simultaneously for demographics, habits, health factors, and use of various medications.Participants were more than 1.1 million men and women from 30 to 102 years of age. The best survival was found among those who slept 7 hours per night. Participants who reported sleeping 8 hours or more experienced significantly increased mortality hazard, as did those who slept 6 hours or less. The increased risk exceeded 15% for those reporting more than 8.5 hours sleep or less than 3.5 or 4.5 hours. In contrast, reports of "insomnia" were not associated with excess mortality hazard. As previously described, prescription sleeping pill use was associated with significantly increased mortality after control for reported sleep durations and insomnia.Patients can be reassured that short sleep and insomnia seem associated with little risk distinct from comorbidities. Slight risks associated with 8 or more hours of sleep and sleeping pill use need further study. Causality is unproven.
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