蓖麻油
聚氨酯
多元醇
乙二醇
六亚甲基二异氰酸酯
异氰酸酯
材料科学
羟基值
高分子化学
固化(化学)
异佛尔酮二异氰酸酯
PEG比率
环氧树脂
生物降解
聚合物
水解
化学工程
有机化学
复合材料
化学
经济
工程类
财务
作者
Hamid Yeganeh,Pejman Hojati-Talemi
标识
DOI:10.1016/j.polymdegradstab.2006.10.011
摘要
Polyurethane networks based on castor oil (CO) as a renewable resource polyol and poly(ethylene glycol) (PEG) with tunable biodegradation rates as potential candidates for biomedical implants and tissue engineering were synthesized through the reaction of epoxy-terminated polyurethane prepolymers (EPUs) with 1,6-hexamethylene diamine curing agent. EPUs themselves were prepared from reaction of glycidol and isocyanate terminated polyurethane prepolymers made from CO or PEG and 1,6-hexamethylene diisocyanate. All of the polymers were characterized by conventional methods, and their physical, mechanical and viscoelastic properties were studied. The results showed that the degradation rate and mechanical properties of final products could be controlled by the ratio of PEG or CO based EPUs in the final products. Increasing the PEG based EPU content caused an increase in hydrolytic degradation rate and mechanical properties. Evaluation of the L-929 fibroblast cells' interaction with prepared polymeric films showed nontoxic behavior and good cytocompatibility.
科研通智能强力驱动
Strongly Powered by AbleSci AI