纳米复合材料
聚乙二醇
材料科学
PEG比率
生物相容性
结晶度
银纳米粒子
傅里叶变换红外光谱
纳米颗粒
化学工程
抗菌剂
复合数
聚乙二醇化
核化学
纳米技术
化学
复合材料
冶金
生物化学
财务
工程类
经济
抗生素
作者
Sinthuran Jegatheeswaran,Shanmugam Muthusubramanian
标识
DOI:10.1016/j.msec.2015.02.012
摘要
Hydroxyapatite (HAp) nanocomposite particles were prepared simply in the presence of polyethylene glycol (PEG) and fabricated with silver via a sol–gel route and the physico-chemical and biological properties of these materials were investigated. The objective of this study is to inspect the crystallinity and antibacterial activity of these composite materials. PEG has been used to greatly promote biocompatibility and biodegradability of HAp. Silver nanoparticles were used for improving its bactericidal efficacy while applying composites. Nano-sized HAp composite particles with PEG and nano-silver was incorporated to increase the crystalline nature of the nanocomposite. The structure of nanocomposite particles was studied by XRD, FTIR, HR-SEM, EDS and TEM analyses. Silver nanoparticles loaded on the synthesized HAp-PEG showed a synergistic antibacterial effect against Gram-negative bacterium Escherichia coli (E. coli). The controlled release of Ag+ ion from HAp-PEG-Ag nanocomposite has given good antibacterial efficacy evidenced by epi-fluorescence microscopy images during different hours.
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