First Total Synthesis of Cleroindicin B, (±) Cleroindicin C and E

Cleroindicin B, C and E, three new natural products originally isolated from Clerodendrum indicum, have been synthesized (in racemic forms for Cleroindicin C and E) by a facile route, starting from 2-(p-methoxy-phenyl) ethanol 1. The (±) cleroindicin C (5) has been resovled by the enantioselective inclusion methodology.