Lateral Flow Assay Based on Molecular Recognition for Diagnosis of Corona Virus Disease 2019 Infection

The novel coronavirus disease 2019(COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) is still spreading worldwide. Rapid screening and isolation of infected individuals, including asymptomatic individuals, is one of the key steps to control the epidemic. Lateral flow assay is a mature technique for point-of-care detection. Owing to its advantages of simple operation, fast response and robustness, lateral flow assay has been a powerful tool for rapid detection of biomarkers. This paper summarized the recent research progresses of lateral flow assays for the diagnosis of COVID-19 infection, with antibody, protein, or nucleic acid as detection targets, and the advantages and limitations of different detection methodologies were shortly discussed. Finally, we briefly introduced the currently commercialized lateral flow test strips for COVID-19 diagnostics. © 2021, Editorial Department of Chem. J. Chinese Universities. All right reserved.