亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

Myopic Choroidal Neovascularization

医学 脉络膜新生血管 黄斑变性 眼科 脉络膜 疾病 黄斑病 人口 血管抑制剂 病态的 验光服务 视网膜病变 外科 贝伐单抗 视网膜 病理 糖尿病 环境卫生 化疗 物理 光学 内分泌学
作者
Chui Ming Gemmy Cheung,Jennifer Arnold,Frank G. Holz,Kyu Hyung Park,Timothy Y. Y. Lai,Michael Larsen,Paul Mitchell,Kyoko Ohno‐Matsui,Shih‐Jen Chen,Sebastián Wolf,Tien Yin Wong
出处
期刊:Ophthalmology [Elsevier BV]
卷期号:124 (11): 1690-1711 被引量:334
标识
DOI:10.1016/j.ophtha.2017.04.028
摘要

The aim of this article is to review and compile available information on the classification, pathophysiology, and clinical features of myopic choroidal neovascularization (CNV); to describe the latest data on the management of this disease; and to present guidance.In the United States, myopia affects approximately 34 million people (2010), and similar figures have been reported in Europe. Pathologic myopia (PM), a possible consequence of myopia, is estimated to affect up to 3% of the global population. One of the most serious complications of PM is myopic CNV, which often leads to a sudden onset but progressive decline in central vision and is associated with a poor prognosis unless treated. Furthermore, 35% of patients with myopic CNV develop bilateral disease in the fellow eye within 8 years. Although intravitreal anti-vascular endothelial growth factor (VEGF) therapies have had a major impact on the management of patients with myopic CNV, there remain significant gaps in our understanding of this condition and how to best administer treatment. Additionally, the long-term safety and efficacy of these treatments are largely unknown.We carried out a literature review (September 2015) of all English-language articles in PubMed resulting from searches of the following terms: "choroidal neovascularization" AND "myopia" OR "myopic macular degeneration" OR "degenerative myopia" OR "myopic maculopathy" OR "myopic retinopathy" OR "pathological myopia" OR "pathologic myopia."We screened a total of 566 abstracts, and 250 articles were deemed relevant for full publication review. We excluded a further 71, but an additional 44 articles were identified. This resulted in 223 articles being used to develop this review.Highly myopic patients experiencing a sudden loss of central vision should be referred for further examination. Once a diagnosis of myopic CNV has been confirmed, after fluorescein angiography, treatment initiation should be prompt and anti-VEGF agents considered as first-line therapy, unless contraindicated. Continued monitoring of patients is required to assess any progression or recurrence of the condition.

科研通智能强力驱动
Strongly Powered by AbleSci AI
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
3秒前
wanci应助科研通管家采纳,获得10
3秒前
3秒前
8秒前
y2k完成签到,获得积分10
9秒前
临子完成签到,获得积分10
10秒前
12秒前
两只棚猫发布了新的文献求助10
15秒前
hanj发布了新的文献求助10
16秒前
风中颖应助qcy72采纳,获得10
24秒前
28秒前
OsamaKareem应助Prof.Z采纳,获得10
29秒前
34秒前
SY发布了新的文献求助10
38秒前
39秒前
两只棚猫完成签到,获得积分10
40秒前
Su发布了新的文献求助10
49秒前
50秒前
LHC888发布了新的文献求助10
55秒前
56秒前
聪明的冥茗完成签到 ,获得积分10
1分钟前
丘比特应助Prof.Z采纳,获得10
1分钟前
蛮21发布了新的文献求助10
1分钟前
LHC888完成签到,获得积分10
1分钟前
Orange应助木子采纳,获得10
1分钟前
Crw__发布了新的文献求助10
1分钟前
SciGPT应助小太阳采纳,获得10
1分钟前
顺利的蚂蚁完成签到,获得积分10
1分钟前
qcy72完成签到,获得积分10
1分钟前
乐乐应助拼搏姒采纳,获得10
1分钟前
科研通AI6.2应助蛮21采纳,获得10
1分钟前
外向的妍完成签到,获得积分10
1分钟前
1分钟前
小太阳完成签到,获得积分10
1分钟前
Moonpie应助duxinyue采纳,获得10
1分钟前
大个应助Prof.Z采纳,获得10
1分钟前
2分钟前
酷波er应助科研通管家采纳,获得10
2分钟前
2分钟前
2分钟前
高分求助中
Overcoming Stigma and Bias in Obesity Management 800
Malcolm Fraser : a biography 700
Signals, Systems, and Signal Processing 610
Bounds for Statistical Estimation in Semiparametric Models 500
Climate change and sports: Statistics report on climate change and sports 500
Forced degradation and stability indicating LC method for Letrozole: A stress testing guide 500
Ideology and Meaning-Making under the Putin Regime 450
热门求助领域 (近24小时)
化学 材料科学 医学 生物 纳米技术 工程类 有机化学 化学工程 生物化学 计算机科学 物理 内科学 复合材料 催化作用 物理化学 光电子学 电极 细胞生物学 基因 无机化学
热门帖子
关注 科研通微信公众号,转发送积分 6471930
求助须知:如何正确求助?哪些是违规求助? 8275933
关于积分的说明 17646185
捐赠科研通 5550704
什么是DOI,文献DOI怎么找? 2909374
邀请新用户注册赠送积分活动 1886159
关于科研通互助平台的介绍 1737057