髓系白血病
癌症研究
白血病
医学
激酶
DNA损伤
癌症
髓样
突变
支票1
酪氨酸激酶
阿糖胞苷
细胞
DNA复制
癌细胞
DNA损伤修复
免疫学
细胞培养
酪氨酸激酶抑制剂
作者
Ping Li,Haiyan Ren,Xinyan Lan,Junfei Li,Zhi Liu,Huashuo Liu,Zhijie Zheng,Tianyan Zeng,Peili Wang,Mingyang Sun,Lei Xu,Yanyan Zhang,Yubo Zhou,Jia Li (160557),Mingliang Wang,Kuncai Jiang
摘要
exhibits synergistic anti-AML effects. Therefore, our findings introduce a promising ATR inhibitor and propose the combination of ATR and FLT3 inhibition as a novel synthetic lethal strategy for treating FLT3-mutated AML.
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(2025-6-4)
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