Natural Synergy-Based Nanosystem Co-Delivering siRNA and Paclitaxel for Full-Stage Apoptosis Promotion in Melanoma

Paclitaxel (PTX) kills tumors cells by stabilizing microtubules to induce apoptosis, but its efficacy is limited by resistance mediated by the anti-apoptotic protein Survivin. Targeting inhibition of Survivin with siRNA...