Study on Anti-fatigue Effect of Polysaccharide of Radix Codonopsis in Mice

Objective To observe the anti-fatigue effect in mice.Methods Different doses(0.8,0.4,0.2g/kg) of the polysaccharide of Radix codonopsis was given to mice for 21 days,the time of loaded-swimming and the content of serum lactic acid were determined.Results The mice treated with different doses of the polysaccharide of Radix codonopsis significantly increased the time of loaded-swimming,and decreased the content of serum lactic acid.Compared with the normal control group,there was significant difference in the high dose group and moderate group(P0.05).Conclusion The polysaccharide of Radix codonopsis can obviously increase the anti-fatigue effect on mice.