Objective:To investigate ulcerative colitis(UC) in clinical characteristics,to treat effective ulcerative colitis.Methods:52 patients with ulcerative colitis patients were treated with the drug system specifications and enema fluid.Results:52 patients with ulcerative colitis condition was under control,obtained satisfactory clinical outcome.Conclusion:The sustained-release tablets plus mesalazine combined with enema for ulcerative colitis can reduce and prevent complications,to achieve the purpose of healing.