At present,diabetic nephropathy(DN)is still the leading cause of end-stage renal disease around the world.While ancient Chinese medicine treatment can do better in improving clinical symptoms,reducing urinary protein and delaying kidney failure and other areas.The main pathogenesis of DN is the deficient fundamental with excessive incidental.The advantage of traditional chinese medicine therapy in treating DN lies in dialectical treatment,staging and classification,and the combination of disease and syndrome differentiation.The essential therapy is supplementing qi,nourishing yin,activating blood and veins,enhancing spleen and kidney and warming yang and excerting water.traditional chinese medicine,Chinese medicine single herbal extracts can improve the clinical symptoms.Compared with western medicine therapy,TCM treats DN from more aspects and the adverse reaction is smaller and safer.traditional chinese medicine is more suitable for people with chronic disease and for long-term use.But it is insufficient of traditional chinese medicine prevention DN,such as the lack of standardized DN diagnosis,typification,efficacy evaluation standard.