Electrochemically driven azide–alkyne cycloaddition (E-CuAAC) via anodic oxidation using dual copper electrodes

A mechanistically accurate and electrochemically driven CuAAC in an undivided cell using dual copper electrodes held at a constant cell voltage of +0.6 V. This setup enables anodic oxidation to promote CuAAC, showing the simplicity of E-CuAAC. The image has been modified with AI (Microsoft Copilot).