Cross-Dehydrogenative Radical Coupling Enabled by K₂S₂O₈: Efficient Synthesis of 2,3-Dicarbonyl Quinolines from Enaminones and Glycine Derivatives

Herein, we report a K₂S₂O₈-mediated metal-free radical dehydrogenative cross-coupling reaction that achieves direct C(sp²)-H/C(sp³)-H radical-radical coupling between N,N-dimethyl enaminones and glycine derivatives. The reaction efficiently proceeds under oxidative conditions via...