Targeted Protein Degradation: From Basic Science to Therapeutic Applications

Targeted protein degradation (TPD) is a groundbreaking approach in molecular therapeutics, enabling the selective elimination of specific proteins by leveraging the cell's own degradation machinery. In November 2024, the SMART Symposium titled "Targeted Protein Degradation: from basic science to therapeutic applications" offered a comprehensive communication on the cutting-edge chemical strategies and emerging clinical applications in this rapidly advancing field.