A UOx@HMnO 2 biozyme–nanozyme driven electrochemical platform for specific uric acid bioassays

, resulting in ultra-high performance. This provides a simple and general method for the preparation of efficient hybridized biocatalysts in the fields of biosensors and biocatalysis. The detection limit of the fabricated uric acid sensor is as low as 0.74 μM, and the concentration of the actual sample is consistent with that of mass spectrometry, which provides a means of non-invasive detection of uric acid with high sensitivity, high specificity and good accuracy.