Abstract Exploring variations in fundamental physics constants across cosmological space-time is of substantial importance in both theoretical and experimental physics. A crucial means of investigating such variations involves comparing laboratory measurements with astrophysical observations. In the present study, we employ a combination of laboratory data and observed Lyman transitions of $$H_2$$ H2 identified in the white dwarf star GD133. Through this examination, we find the temporal variation of the gravitational constant, $${{\dot{G}}}/{G} = (0.016 \pm 0.098) \times 10^{-15}~\text {year}^{-1}$$ G˙/G=(0.016±0.098)×10-15year-1 with a gravitational potential $$\phi \approx 10^4,$$ ϕ≈104, and an average total redshift of $$H_2,$$ H2, $$z_{abs} =0.0001820(10).$$ zabs=0.0001820(10). This newly determined constraint on the time variation of G serves as an important tool for advancing discussions within unified theories.