自噬
贝肯1
程序性细胞死亡
生物
癌症研究
免疫
肿瘤微环境
细胞生物学
免疫系统
肿瘤细胞
免疫学
细胞凋亡
遗传学
作者
Yuyan Xie,Yang Zhou,Jiale Wang,Lili Du,Yuanyuan Ren,Fang Liu
出处
期刊:Heliyon
[Elsevier]
日期:2023-09-01
卷期号:9 (9): e19799-e19799
标识
DOI:10.1016/j.heliyon.2023.e19799
摘要
Ferroptosis was first proposed in 2012, a new form of cell death. Autophagy plays a crucial role in cell clearance and maintaining homeostasis. Autophagy is involved in the initial step of ferroptosis under the action of histone elements such as NCOA4, RAB7A, and BECN1. Ferroptosis and autophagy are involved in tumor progression, treatment, and drug resistance in the tumor microenvironment. In this review, we described the mechanisms of ferroptosis, autophagy, and tumor and immunotherapy, respectively, and emphasized the relationship between autophagy-related ferroptosis and tumor.
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