化学
席夫碱
铜
苯胺
核化学
二茂铁
镍
钴
氨基脲
元素分析
傅里叶变换红外光谱
尿素酶
有机化学
高分子化学
酶
物理
电极
物理化学
量子力学
电化学
作者
Rukhsana Gul,Wajid Munir,Ebraheem Abdu Musad Saleh,Shaukat Shajah,Muhammad Sirajuddin,Saira Tabassum,Khalil Ur-Rehman,Dilfaraz Khan,Sameerah I. Al‐Saeedi,Ehab A. Abdelrahman
标识
DOI:10.1016/j.jorganchem.2023.122944
摘要
Two new Schiff base ligands were synthesized by the reaction of ferrocenyl aniline with aromatic aldehydes which were used for the formation of copper, nickel, and cobalt complexes. The synthesized compounds were characterized by elemental analysis, UV-Visible, FTIR, 1H, and 13C-NMR Spectroscopy. The synthesized compounds were screened for various biological activities. The compounds showed moderate to significant activities. From the result, it was clear that metal complexes exhibited significantly better activities than their parent ligands. For anti-bacterial activities, the disk diffusion method was used. In all synthesized compounds, Nickel complexes showed higher results against S. setubal. In anti-fungal activities, Sb1Ni(II) and Sb2Cu(II) showed good results against M. species and F. solani respectively. Copper complexes of both Schiff bases showed good anti-diabetic and antioxidant activities. Copper Complex (Sb1, Sb2) exhibited considerable inhibition against α-Amylase (50.12%, 33.20%), Urease (49.12%, 47.20%), and Lipase (49.12%, 42.20%) as well as remarkable antioxidant activities (45.22% and 52.12%) in DPPH assay respectively.
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