Association between coronary plaque vulnerability features and multiparametric pericoronary fat indices on coronary computed tomography angiography: a cross-sectional study

Among the five PCAT indices, the FAI and non-FAI demonstrated stronger associations with plaque vulnerability features, whereas VPCI, PVWI, and FV showed weaker associations. Vulnerable plaque features (PR, LAP) induced more severe inflammatory responses in PCAT compared to PC and NRS. Additionally, PCAT indices were influenced by the lesion-bearing vessel. These findings may guide clinical prioritization of inflammatory biomarkers and refine assessments of plaque-related inflammation severity.