肺表面活性物质
聚山梨酯
聚乙烯醇
色谱法
悬挂(拓扑)
化学
材料科学
化学工程
有机化学
同伦
数学
生物化学
工程类
纯数学
作者
Jamie T. Konkel,Allan S. Myerson
标识
DOI:10.1080/08927020802512195
摘要
Molecular modelling has been used successfully to predict the stabilisation of crystalline nanosuspensions of model pharmaceutical drugs by the surfactant Polysorbate 80. The ratio of the binding energy of the Polysorbate 80 to the binding energy of the drug to the surface of the crystal was found to correlate with the stabilisation of the nanosuspension.
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