Lactiplantibacillus plantarum HEAL9 attenuates cognitive impairment and progression of Alzheimer's disease and related bowel symptoms in SAMP8 mice by modulating microbiota-gut-inflammasome-brain axis

HEAL9 alleviates cognitive decline and normalizes colonic motility in the prodromal AD via microbiota-gut-inflammasome-brain axis. HEAL9 can represent a suitable therapeutical option for the treatment of early AD and related intestinal symptoms.