Effects of strengthen intervention of community groups in Nanning city blood pressure with longitudinal follow-up study

Objective To understand the impact of blood pressure and the cardiovascular-cerebrovascular events through comprehensive drug intervention of community hypertension groups.Methods We used a random cluster sampling of Nanning City in line with the two communities included in the standard 1215 as an integrated intervention in the treatment of subjects,which were randomly divided into strengthening intervention and control groups.Strengthen the intervention groups which according to whether or not people suffer from hypertension and related diseases,were taken to strengthen the different treatment intervention;in the control group remained voluntary medical staff and volunteers taking care of the normal state,follow up 3 years to the CVD events.Results The forward-looking follow-up study after 43.5 months①as compared with the two groups of hypertension patients with systolic and diastolic blood pressure significantly lower than the pre-intervention.(P0.01);and the intervention group patients with systolic blood pressure than the control group declined even more significantly(P0.05);②to compare with pre-intervention blood glucose significantly lower and uric acid higher than those;the weight,fasting insulin,BMI and LDL of intervention group more significantly decreased than pre-intervention;and waist circumference,cholesterol and triglycerides decreased after the intervention of 1.5 years,but rebound after 3 years;the weight,waist circumference,cholesterol and triglyceride of control group,decrease not obvious.③the blood pressure control rate of both two groups significantly higher than before the intervention(P0.01);and the intervention group was significantly higher than the control group(P0.001),the two new hypertension rates go down year by year,but there is no significant difference on statistics(P=0.054).④the rate of cardiovascular-cerebrovascular events on this study was 4.0 percent,which of hypertension patients was significantly higher than those of non-hypertension(6.9% VS 2.9%,P=0.003).Among the control group,whether hypertension or non-hypertension the rates are significantly higher than the intervention group(P0.001 or P0.05).Conclusion Comprehensive drug intervention can significantly decrease blood pressure,and related groups metabolic levels of community hypertension group,reduce the incidence of new hypertension and the risk of cardiovascular-cerebrovascular events.