Clinical significance analysis of peripheral blood levels of soluble CD147 detection for patients with hyperlipidemia

Objective To analyze the correlation between soluble CD147(sCD147) and hyperlipidemia by detecting the sCD147 expression level in peripheral blood among hyperlipidemia patients,and to provide technical indicators for the clinical diagnosis of hyperlipidemia.Methods Enzyme-linked immunosorbent assay was used to measure the sCD147 in 367 sporadic hyperlipidemia patients and in 212 healthy people.Results The sCD147 expression level in hyperlipidemia group was(7.68±1.53)ng/L,in healthy control group was(2.78±0.52)ng/L,and the difference was statistically significant(P0.001).Conclusion sCD147 might behave positive correlation with hyperlipidemia,and it could be used as new indicators for the clinical diagnosis of hyperlipidemia.